He left home when he was thirteen to escape an abusive stepfather and followed local R&B guitarist, "Little Melvin" Underwood through the Chitlin Circuit, first as his valet and then as lead vocalist himself at 15.

While singing at the 506 Club in Pensacola, Florida he was introduced to Producer/ DJ, "Papa Don" Schroeder and in 1966, Sam recorded Patsy Cline's "Sweet Dreams" - his first real success. Several recording sessions at Muscle Shoals produced singles, "Fannie-May" and "In the Same Old Way". For
fifteen years, first in Nashville, then in New Orleans Sam worked menial jobs and was forced to sell his plasma while he was homeless. From cotton fields to the Apollo Theater to the park bench, all while living the songs that would jump-start his career in the mid-1980. New Orleans own, Neville Brothers extended themselves at this lowest of times. Sam was offered a chance to tour and record in Japan in 1989. "Live in Japan", featuring legendary Wayne Bennett is a fine recording, much sought after by fans worldwide.

By the early 1990's Sam networked his way to New England through his participation in the "Hubert Sumlin Blues Party" project (produced by Hammond Scott on Black Top), which involved many Boston based musicians. These friends provided encouragement and collaborations, which led to Joe Harley and AudioQuest Music. The results were the successful releases, "Give It Up To Love" and "Keep On Movin". After his move to New Hampshire the momentum continued to build with "Sledgehammer Soul and Down Home Blues". In 1998 Sam had two releases, "Journey" (AQM) and "Joy and Pain -Live in Europe" on the CrossCut label. "Soul Survivor -The Best of MSM" was his farewell to AudioQuest in 1999. ("Journey" and "Soul Survivor" both include "New Man in Town", featured on David E. Kelley's Ally McBeal on FOX-TV). Sam signed on with the Telarc Blues label in 1999, taking his longtime producer Joe Harley with him and recorded W.C. Handy nominated "Blues for the Soul in 2000 and "Sweet Dreams" in 2001 (also Handy nominated)
Sam started to take back his career in 1996 and turned to managing himself. His publishing company, Emily's Son Publishing, has been licensed since 1993 when his original work appeared on "Give "It Up To Love". McClain formed McClain Productions after successfully co-producing his CD's with Joe Harley. And now, the last step of his independence has been realized through the creation of his own label, Mighty Music which  release his CD "One More Bridge To Cross" in February 2003. His newest project, "Betcha Didn't Know" which reveals yet another side of MSM was released in July 2009 on Mighty Music  with City Hall Records as the distributor. Sam greatly appreciated the nomination of this CD by The Blues Association as "Soul/Blues Album 2010". You can find it in a store near you or order it directly from our web store - stop by and listen!

2008 brought Sam into the "Give US Your Poor" project, benefiting the homeless. He co-wrote (with saxophonist Scott Shetler) "Show Me the Way", which was included in the compilation where he and Jon Bob Jovi sung this stirring anthem as a duet. He continues to work with this project, performing at both The Lincoln Center, New Your City and at The Kennedy Center in Washington and other venues, sharing the stage with Natalie Merchant, and the smashing Greek tenor, Mario Frangoulis as well as the others mentioned on the CD. In early 2009, MSM was asked to record a CD of duets with Iranian folk vocalist Mahsa Vadhat. The resulting CD, "Scent of Reunion-Love Duets Across Civilizations" (www.kkv.no) reached #6 in the European World Music Charts and this is a Mighty Sam McClain that has never been heard before! Mahsa and Sam have had concerts in Norway to celebrate this music. Sam and the guitarist for this project, Knut Reisersrud, are collaborating on a CD that will be recorded in Norway in January 2011. Also, Sam has  sung the theme song for Ernest Thompson, (the Oscar winner for "On Golden Pond") for his new film, "Time and Change$. "Find the Sun" is a song written by Thompson and Joe Deleault (keyboards in MSM's band) but is recognizable a song that Sam has made his own.  Furthermore, he will have a cameo in the film, singing it! To top it of, Sam has recorded another CD-ready to go, called "Too Much Jesus (Not Enough Whiskey)" and the next music in  the works. Pat Herlehy (Sam's guitarist) and MSM have a deep connection that is producing some great music.

Mighty Sam McClain is in control - of his life and career as he continues to perform nationally and internationally. It's full steam ahead for this great vocalist! "The Soul of America" is what he is called in Europe - he is, just as his lyrics describe, "I'm a singer, a man with a song.and I've got a message for you."